| Cluster ID | Structural Fold | #SEQ | Pfam Domain | CATH (Representative) | SCOP (Representative) |
"
AC_001 |  | 244 | Gamma-thionin
Defensin_2
Toxin_3
Toxin_37
Toxin_2
Antimicrobial_6 | [C] Alpha Beta
[A] 2-Layer Sandwich
[T] Defensin A-like
| [C] Small proteins
[F] Knottins (small inhibitors, toxins, lectins)
[S] Scorpion toxin-like
[F] Plant defensins
|
AC_002 |  | 40 | IL8 | [C] Mainly Beta
[A] Beta Barrel
[T] OB fold (Dihydrolipoamide Acetyltransferase, E2P)
| [C] Alpha and beta proteins (a+b)
[F] IL8-like
[S] Interleukin 8-like chemokines
[F] Interleukin 8-like chemokines
|
AC_003 |  | 111 | Moricin
CAP18_C
Hormone_2
Antimicrobial_2
DD_K
Antimicrobial12
Defensin_big | [C] Mainly Alpha
[A] Up-down Bundle
[T] Single alpha-helices involved in coiled-coils or other helix-helix interfaces
[H] Single helix bin
| [C] Peptides
[F] Antimicrobial helix
[S] Antimicrobial helix
[F] Moricin
|
AC_004 |  | 48 | Defensin_beta
Defensin_1
| [C]
[A]
[T]
| [C] Small proteins
[F] Defensin-like
[S] Defensin-like
[F] Defensin
|
AC_005 |  | 52 | Cyclotide | [C]
[A]
[T]
| [C] Small proteins
[F] Knottins (small inhibitors, toxins, lectins)
[S] Cyclotides
[F] Kalata B1
|
AC_006 |  | 25 | Histone
| [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Histone, subunit A
[H] Histone, subunit A
| [C] All alpha proteins
[F] Histone-fold
[S] Histone-fold
[F] Nucleosome core histones
|
AC_007 |  | 23 | Lys | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Lysozyme
| [C] Alpha and beta proteins (a+b)
[F] Lysozyme-like
[S] Lysozyme-like
[F] C-type lysozyme
|
AC_008 |  | 13 | Thionin | [C] Alpha Beta
[A] 2-Layer Sandwich
[T] Crambin
[H] Crambin-like
| [C] Small proteins
[F] Crambin-like
[S] Crambin-like
[F] Crambin-like
|
AC_009 |  | 22 | SapB_2
SapB_1
Bacteriocin_IId | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] NK-Lysin
[H] Saposin
| [C] All alpha proteins
[F] Saposin-like
[S] Saposin
[F] NKL-like
|
AC_010 |  | 21 | RnaseA | [C] Alpha Beta
[A] Roll
[T] P-30 Protein
[H] P-30 Protein
| [C] Alpha and beta proteins (a+b)
[F] RNase A-like
[S] RNase A-like
[F] Ribonuclease A-like
|
AC_011 |  | 8 | Tachystatin_A
Antifungal_pept
Tachystatin_B | [C] Few Secondary Structures
[A] Irregular
[T] Omega-AgatoxinV
| [C] Small proteins
[F] Knottins (small inhibitors, toxins, lectins)
[S] omega toxin-like
[F] Spider toxins
|
AC_012 |  | 14 | Phospholip_A2_1 | [C] Mainly Alpha
[A] Up-down Bundle
[T] Phospholipase A2
[H] Phospholipase A2
| [C] All alpha proteins
[F] Phospholipase A2, PLA2
[S] Phospholipase A2, PLA2
[F] Vertebrate phospholipase A2
|
AC_013 |  | 28 |
Transferrin | [C] Alpha Beta
[A] 3-Layer(aba) Sandwich
[T] D-Maltodextrin-Binding Protein; domain 2
[H] Periplasmic binding protein-like II
| [C] Alpha and beta proteins (a/b)
[F] Periplasmic binding protein-like II
[S] Periplasmic binding protein-like II
[F] Transferrin
|
AC_014 |  | 2 | | [C]
[A]
[T]
| [C]
[F]
[S]
[F]
|
AC_015 |  | 2 | Lectin_legB | [C] Mainly Beta
[A] Sandwich
[T] Jelly Rolls
| [C]
[F]
[S]
[F]
|
AC_016 |  | 3 | WAP | [C]
[A]
[T]
| [C]
[F]
[S]
[F]
|
AC_017 |  | 4 | | [C]
[A]
[T]
| [C]
[F]
[S]
[F]
|
AC_018 |  | 7 | Chitin_bind_1 | [C] Alpha Beta
[A] 2-Layer Sandwich
[T] Wheat Germ Agglutinin (Isolectin 2); domain 1
| [C] Small proteins
[F] Knottins (small inhibitors, toxins, lectins)
[S] Plant lectins/antimicrobial peptides
[F] Hevein-like agglutinin (lectin) domain
|
AC_019 |  | 6 | Myotoxins
| [C] Mainly Beta
[A] Single Sheet
[T] Anthopleurin-A
[H] Anthopleurin-A
| [C] Small proteins
[F] Defensin-like
[S] Defensin-like
[F] Myotoxin
|
AC_020 |  | 7 | Thaumatin
| [C] Mainly Beta
[A] Sandwich
[T] Thaumatin
[H] Thaumatin
| [C] All beta proteins
[F] Osmotin, thaumatin-like protein
[S] Osmotin, thaumatin-like protein
[F] Osmotin, thaumatin-like protein
|
AC_021 |  | 6 | Amidase_2 | [C] Alpha Beta
[A] 3-Layer(aba) Sandwich
[T] Lysozyme-like
[H] Lysozyme
| [C] Alpha and beta proteins (a+b)
[F] N-acetylmuramoyl-L-alanine amidase-like
[S] N-acetylmuramoyl-L-alanine amidase-like
[F] N-acetylmuramoyl-L-alanine amidase-like
|
AC_022 |  | 9 |
Tryp_alpha_amyl | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Hydrophobic Seed Protein
[H] Plant lipid-transfer and hydrophobic proteins
| [C]
[F]
[S]
[F]
|
AC_023 |  | 2 | zf-C2H2 | [C]
[A]
[T]
| [C] Designed proteins
[F] Zinc finger design
[S] Zinc finger design
[F] Zinc finger design
|
AC_024 |  | 6 | Thi4
Amino_oxidase | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Guanine Nucleotide Dissociation Inhibitor; domain 1
[H] Guanine Nucleotide Dissociation Inhibitor, domain 1
| [C] Alpha and beta proteins (a/b)
[F] FAD/NAD(P)-binding domain
[S] FAD/NAD(P)-binding domain
[F] FAD-linked reductases, N-terminal domain
|
AC_025 |  | 2 | S_100 | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Recoverin; domain 1
[H] EF-hand
| [C] All alpha proteins
[F] EF Hand-like
[S] EF-hand
[F] S100 proteins
|
AC_026 |  | 6 | MiAMP1
Crystall_2 | [C] Mainly Beta
[A] Sandwich
[T] Gamma-B Crystallin; domain 1
| [C] All beta proteins
[F] gamma-Crystallin-like
[S] gamma-Crystallin-like
[F] Plant antimicrobial protein MIAMP1
|
AC_027 |  | 5 | Chitin_bind_1
Glyco_hydro_19 | [C] Mainly Alpha
[A] Orthogonal Bundle
[T] Lysozyme
| [C] Alpha and beta proteins (a+b)
[F] Lysozyme-like
[S] Lysozyme-like
[F] Family 19 glycosidase
|
AC_028 |  | 30 | Trypsin
Peptidase_S29 | [C] Mainly Beta
[A] Beta Barrel
[T] Thrombin, subunit H
[H] Trypsin-like serine proteases
| [C] All beta proteins
[F] Trypsin-like serine proteases
[S] Trypsin-like serine proteases
[F] Eukaryotic proteases
|
AC_029 |  | 6 | Antifungal_prot | [C] Mainly Beta
[A] Beta Barrel
[T] OB fold (Dihydrolipoamide Acetyltransferase, E2P)
| [C] Small proteins
[F] Antifungal protein (AGAFP)
[S] Antifungal protein (AGAFP)
[F] Antifungal protein (AGAFP)
|
AC_030 |  | 3 | Neocarzinostat | [C] Mainly Beta
[A] Sandwich
[T] Immunoglobulin-like
| [C] All beta proteins
[F] Immunoglobulin-like beta-sandwich
[S] Actinoxanthin-like
[F] Actinoxanthin-like
|
